Change 1st cousins to 2nd cousins in Table 2.

Mohamed Hrira Yahia — 2012-01-05T11:56:34Z

I comet a mistake, I will like to correct it.
I will like to correct this mistake. These patients were offspring of consanguineous marriage of second degree. The parents of this family have the same grandfather with different wife.

Typographical error

Hongxiu Han — 2012-01-05T11:41:20Z

The data 97.2% shown in the article should be 96.9%. We apologize for the oversight.

On number of sections and statistical power

Vincenzo Della Mea — 2009-02-10T09:18:10Z

After having attended the Authors' congress presentation, I read the paper with much interest, because it depicts very well a protocol for obtaining reliable results from image analysis on histological sections.

However I would like to point out that the section entitled "Number of sections has little influence on statistical power of the study" reports a result well known since many years: statistical accuracy of a study depends more on the number of subjects enrolled than on the number of samples within the same subject, according to the Gundersen expression “Do more less well” (1). When dealing with rare condition, taking more samples from few subjects seems a shortcut for obtaining statistically significant results, but is not always the case.

(1) Gundersen HJG, Osterby R. Optimizing sampling efficiency of stereological studies in biology: or “do more less well!”. J Microsc 1981; 121-65.

Diagnostic Pathology - Latest Comments

Change 1st cousins to 2nd cousins in Table 2.

Typographical error

On number of sections and statistical power