Table 4

Correlation between miR-143 expression and cervical SCC clinical pathological features
Clinical characters Cases (n) miR-143 expression Z P
Cervical SCC −2.180 0.029*
No 20 1.000 (0.241-1.878)
Yes 77 0.280 (0.059-1.050)
Age (years old) −1.236 0.217
≤ 50 41 0.259 (0.143-0.707)
> 50 36 0.337 (0.167-1.092)
Clinical Stage 2.673 0.263
I 16 0.387 (0.176-1.258)
II 43 0.268 (0.131-0.698)
III-IV 18 0.287 (0.155-0.905)
Pathological Grade −1.142 0.253
Well differentiation 27 0.320 (0.198-0.859)
Moderate and poor differentiation 50 0.258 (0.118-1.052)
Lymph node metastasis −2.293 0.022*
No 43 0.578 (0.209-1.384)
Yes 16 0.175 (0.103-0.544)
Tumor diameter −2.705 0.007*
≤ 4 cm (smaller tumor) 54 0.345 (0.112-1.490)
> 4 cm (larger tumor) 23 0.125 (0.103-0.459)
LVSI −0.567 0.571
No 46 0.294 (0.159-1.075)
Yes 13 0.607 (0.293-1.501)
HPV infection 9.050 0.011*
HPV negative 17 1.053 (0.289-1.412)
HPV16 infection (single or multiple) 32 0.230 (0.105-0.496) −2.647 0.008*
Other genotype HPV infection 28 0.524 (0.109-1.233) −1.651 0.099

Note: *P < 0.05. in comparison with HPV negative group.

SCC, squamous cell carcinoma; LVSI, lymph vascular space invasion.

Chen et al.

Chen et al. Diagnostic Pathology 2014 9:88   doi:10.1186/1746-1596-9-88

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