Table 1

Associations between the status of CD44 variants and CD44s and the categorical clinicopathological parameters of pancreatic carcinoma (n = 101)
Parameters CD44v2 CD44v3 CD44v4 CD44v5 CD44v6 CD44v7 CD44v8 CD44v9 CD44v10 CD44s
+ - + - + - + - + - + - + - + - + - + -
Gender
 P-value 0.379 0.379 0.956 0.68 0.956 0.178 0.956 0.956 0.322 0.379
 Male/Female 40/10 37/14 40/10 37/14 39/12 38/12 39/11 38/13 39/12 38/12 41/9 36/15 38/12 39/12 39/12 38/12 41/10 36/14 40/10 37/14
Age, years
 P-value 0.875 0.551 0.551 0.777 0.777 0.551 0.551 0.777 0.47 0.551
 <65/≥65 36/14 36/15 37/13 35/16 37/13 35/16 35/15 37/14 37/14 35/15 37/13 35/16 37/13 35/16 37/14 35/15 38/13 34/16 37/13 35/16
Tumor location
 P-value 0.353 0.796 0.737 0.737 0.796 0.796 0.796 0.737 0.737 0.353
 Head/Body,tail 42/8 46/5 44/6 44/7 45/6 43/7 43/7 45/6 44/7 44/6 44/6 44/7 44/6 44/7 45/6 43/7 45/6 43/7 42/8 46/5
Tumor size, cm
 P-value 0.9 0.593 0.489 0.346 0.489 0.9 0.9 0.9 0.593 0.271
 ≤2/>2 19/31 20/31 18/32 21/30 18/33 21/29 17/33 22/29 18/33 21/29 19/31 20/31 19/31 20/31 20/31 19/31 21/30 18/32 22/28 17/34
Lymphatic invasion
 P-value 0.625 0.197 0.055 0.197 0.02 0.09 0.09 0.02 0.129 0.474
 Neg/Pos 27/23 30/21 25/25 32/19 24/27 33/17 25/25 32/19 23/28 34/16 24/26 33/18 24/26 33/18 23/28 34/16 25/26 32/18 30/20 27/24
Vascular invasion
 P-value 0.006 0.408 0.408 0.702 0.951 0.408 0.951 0.702 0.951 0.203
 Neg/Pos 30/20 43/8 38/12 35/16 35/16 38/12 37/13 36/15 37/14 36/14 38/12 35/16 36/14 37/14 36/15 37/13 37/14 36/14 39/11 34/17
Neural invasion
 P-value 0.875 0.875 0.777 0.3 0.875 0.777 0.551 0.245 0.875 0.47
 Neg/Pos 36/14 36/15 36/14 36/15 37/14 35/15 38/12 34/17 36/15 36/14 35/15 37/14 37/13 35/16 39/12 33/17 36/15 36/14 34/16 38/13
Duodenal invasion
 P-value 0.295 0.583 0.653 0.653 0.295 0.295 0.653 0.583 0.961 0.147
 Neg/Pos 38/12 43/8 39/11 42/9 40/11 41/9 41/9 40/11 43/8 38/12 38/12 43/8 41/9 40/11 42/9 39/11 41/10 40/10 43/7 38/13
Hepatic metastases
 P-value 0.484 0.042 0.049 0.172 0.049 0.049 0.042 0.049 0.049 0.049
 Neg/Pos 44/6 47/4 42/8 49/2 43/8 48/2 43/7 48/3 43/8 48/2 43/7 48/3 42/8 49/2 43/8 48/2 43/8 48/2 48/2 43/8
Differentiation
 P-value 0.808 0.1 0.507 0.124 0.202 0.927 0.491 0.696 0.428 0.028
 Poor 13 16 18 11 17 12 19 10 15 14 14 15 15 14 13 16 16 13 11 18
 Middle 32 31 26 37 29 34 27 36 29 34 31 32 29 34 32 31 29 34 31 32
 Well 5 4 6 3 5 4 4 5 7 2 5 4 6 3 6 4 6 3 8 1
Stage (UICC)
 P-value 0.837 0.109 0.057 0.135 0.008 0.286 0.061 0.027 0.143 0.028
 IA/IB 4/11 6/14 3/13 7/12 2/12 8/13 2/13 8/12 2/13 8/12 3/12 7/13 4/12 6/13 4/11 6/14 4/12 6/13 6/18 4/7
 IIA/IIB 9/20 6/20 4/22 11/18 5/24 10/16 5/23 10/17 3/25 12/15 5/23 10/17 3/23 12/17 3/25 12/15 4/23 11/17 4/19 11/21
 III/IV 0/6 0/5 0/8 0/3 0/8 0/3 0/7 0/4 0/8 0/3 0/7 0/4 0/8 0/3 0/8 0/3 0/8 0/3 0/3 0/8

The bold values indicate P-values less than 0.05, Neg (−): negative, Pos(+): positive, UICC Union for International Cancer Control.

Li et al.

Li et al. Diagnostic Pathology 2014 9:79   doi:10.1186/1746-1596-9-79

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