Table 2

Characteristics of eligible studies in this meta-analysis
First author (year) Country Ethnicity Genotyping methods Source of controls Sample size (case/control) Matching variables Prostate cancer diagnosis QC when genotyping PI HWE (P value) Quality scores
−308G/A −238G/A
Ribeiro (2012) Portugal Caucasia TaqMan HB 449/557 Age HC No −308G/A 0.155 - 10
Berhane (2012) India (N) Asia ARMS-PCR HB 150/150 Age HC No −308G/A 0.662 - 10
Wang (2009) America (W) mixed TaqMan PB 251/250 Age, sex,ethnicity HC No −308G/A 0.529 - 12
Moore (2009) Finland (W) mixed TaqMan PB 949/857 Age, sex HC Yes −308G/A 0.231 - 14
Kesarwani (2009) India (E) Asia PCR-RFLP PB 197/256 Age, sex, ethnicity HC Yes −308G/A 0.115 - 13
Zabaleta 1 (2008) America (W) Caucasia TaqMan HB 950/785 Ethnicity HC Yes −308G/A,-238G/A 0.505 0.295 10
Zabaleta 2 (2008) America (W) African-American TaqMan HB 131/256 Ethnicity HC Yes −308G/A,-239G/A 0.959 0.006 8
Sáenz-López (2008) Spain Caucasia TaqMa HV 296/310 Ethnicity HC No −308G/A 0.715 - 9
Danforth 1 (2008) America (W) Caucasia TaqMan PB 1155/1389 Age HC Yes −308G/A 0.795 - 14
Danforth 2 (2008) America (W) Caucasia TaqMan PB 2225/2251 Age HC Yes −308G/A,-239G/A 0.217 0.737 14
Ge (2007) China Asia TaqMan HB 490/490 Age HC + PC No −308G/A 0.609 0.462 11
Wu (2004) China Asia PCR HV 96/126 Sex HC No −308G/A,-239G/A 0.883 - 7
McCarron (2002) UK Caucasia PCR HB 239/220 Ethnicity HC No −308G/A 0.023 - 7
OH (2000) America Caucasia PCR HB 146/244 Ethnicity PC Yes −308G/A,-239G/A 0.554 0.091 9

PI, Polymorphism(s) investigated; QC, Quality control; NA, Not available; PB, Population–based; HB, Hospital–based; HV, healthy-volunteers; HC, Histologically confirmed; PC, Pathologically confirmed; HWE, Hardy–Weinberg equilibrium in control population.

Ma et al.

Ma et al. Diagnostic Pathology 2014 9:74   doi:10.1186/1746-1596-9-74

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