Table 1

Scale for quality assessment
Criteria Score
1. Representativeness of cases
Selected from population or cancer registry 3
Selected from hospital 2
Selected from pathology archives, but without clearly defined sampling frame or with extensive inclusion/exclusion criteria 1
Not described 0
2. Source of controls
Population- based 3
Blood donors or volunteers 2
Hospital-based (cancer -free patients) 1
Not described 0
3. Pecimens of cases determining genotypes
White blood cells or normal tissues 1
Tumor tissues or exfoliated cells of tissue 0
4. Ascertainment of prostate cancer
Histopathologic confirmation 2
Diagnosis of prostate cancer by patient medical record 1
Not described 0
5. Total sample size
≧1000 3
≧400 but <1000 2
≧200 but <400 1
<200 0
6. Hardy-Weinbe rg equilibrium in controls
Hardy-Wei nberg equilibrium 1
Hardy-Wei nberg disequilibrium 0
7. Quality control of genotyping methods
Repetition of partial/total tested samples 1
Not described 0 0

Ma et al.

Ma et al. Diagnostic Pathology 2014 9:74   doi:10.1186/1746-1596-9-74

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