## Table 2 |
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Allelic and genotypic associations between three selected SNPs and AMD |
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SNP information |
Allelic associations |
Genotypic associations |
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dbSNP ID |
Gene |
chr:pos |
Location |
Alleles^{a} |
Effective allele frequency |
P value^{b} |
Genotypic distributions |
P value^{c} |
P value^{d} |
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OR (95% CI) |
OR (95% CI) |
OR (95% CI) |
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rs2842992 | SOD2 |
6:160071159 | Intergenic | A/G |
Case | 0.523 | GA case | 0.547 | 0.277 | AA/AG/GG | Case | 47/107/38 | 0.266 | 0.661 |

Control | 0.558 | Non-GA case | 0.508 | 0.87 (0.67-1.13) | Control | 109/165/69 | 0.87 (0.67-1.12) | 0.93 (0.68-1.28) | ||||||

rs1789110 | MBP |
18:74859044 | Intergenic | A/C |
Case | 0.542 | GA case | 0.533 | 0.850 | AA/AC/CC | Case | 55/107/38 | 0.798 | 0.537 |

Control | 0.535 | Non-GA case | 0.548 | 1.03 (0.80-1.33) | Control | 100/171/76 | 1.03 (0.80-1.33) | 1.10 (0.81-1.51) | ||||||

rs722782 | C80rf42 |
8:516479 | Intergenic | A/C |
Case | 0.473 | GA case | 0.471 | 0.281 | AA/AC/CC | Case | 43/92/53 | 0.279 | 0.080 |

Control | 0.508 | Non-GA case | 0.475 | 0.87 (0.67-1.12) | Control | 97/177/91 | 0.87 (0.68-1.12) | 0.76 (0.56-1.03) |

*Abbreviations*: *chr:pos* chromosome:position, *OR* odds ratio, *CI* confidence interval.

^{a}Effective alleles are indicated in bold type, and odds ratios were calculated based
on this allele.

^{b}ORs, 95% CIs and P values were calculated based on Fisherâ€™s exact test.

^{c}ORs, 95% CIs and P values were calculated using logistic regression, assuming the
additive model.

^{d}ORs, 95% CIs and P values were calculated using logistic regression, assuming the
additive model with adjustment for age.

Kan * et al.*

Kan * et al.* *Diagnostic Pathology* 2014 **9**:73 doi:10.1186/1746-1596-9-73