Table 2

Univariate survival analysis of osteosarcoma according to immunohistochemistry scores for HLA class I and other clinicopathologic factors
3 year overall survival rate 3 year disease free survival rate
HLA class I P < 0.0001 P < 0.0001
   Negative 0% 0%
   Low 77.8% 33.3%
   High 100% 66.1%
Age P = 0.93 P = 0.89
   ≤ 14 years 83.3% 33.3%
   > 14 years 60.4% 44.4%
Sex P = 0.023 P = 0.001
   Male 80.9% 51.9%
   Female 0% 0%
Tumor site P = 0.60 P = 0.081
   Lower femur 85.7% 38.1%
   Middle femur 0% 0%
   Upper tibia 58.3% 66.7%
Tumor stage P < 0.0001 P < 0.0001
   Localized 96.3% 51.9%
   Metastatic 0% 0%
Histopathological variant P = 0.13 P = 0.413
   Osteoblastic 39.3% 50%
   Chondroblastic 37.5% 25%
   Fibroblastic 100% 55.6%
   Small cell type 100% 0%
Tumor necrosis P = 0.017 P < 0.0001
   Poor response (<90%) 32.7% 12.5%
   Good response (≥90%) 100% 91.7%

Nada et al.

Nada et al. Diagnostic Pathology 2014 9:72   doi:10.1186/1746-1596-9-72

Open Data