Table 2

Expression of HOXB7 mRNA, protein, and miR-337 in the pancreatic ductal adenocarcinoma cases
Parameter HOXB7 protein HOXB7 mRNA miR-337
Negative (n) Positive (n) P value Expression level P value Expression level P value
Gender
 Male 10 18 0.764 1.319 ± 0.221 0.795 0.2900 ± 0.09854 0.860
 Female 5 11 1.302 ± 0.218 0.2981 ± 0.08573
Age (years)
 <60 9 17 0.930 1.296 ± 0.229 0.631 0.306 ± 0.105 0.132
 ≥60 6 12 1.338 ± 0.203 0.274 ± 0.072
Diameter(cm)
 <4 14 19 0.043* 1.259 ± 0.219 0.033* 0.305 ± 0.097 0.228
 ≥4 1 10 1.474 ± 0.107 0.257 ± 0.072
Location
 Head 12 19 0.398 1.308 ± 0.222 0.690 0.304 ± 0.095 0.521
 Body or tail 3 9 1.325 ± 0.215 0.263 ± 0.084
Differentiation
 Well 6 3 0.009** 1.221 ± 0.142 0.028* 0.312 ± 0.082 0.210
 Moderate 9 16 1.279 ± 0.243 0.305 ± 0.102
 Poor 0 10 1.481 ± 0.084 0.245 ± 0.066
TNM stage
 I or II 11 9 0.008** 1.161 ± 0.214 0.010* 0.338 ± 0.109 0.002**
 III or IV 4 20 1.440 ± 0.117 0.256 ± 0.057
Nodal status
 Negative 12 12 0.015* 1.199 ± 0.220 0.014* 0.330 ± 0.105 0.001**
 Positive 3 17 1.450 ± 0.111 0.248 ± 0.048

*P <0.05, **P <0.01.

Zhang et al.

Zhang et al. Diagnostic Pathology 2014 9:61   doi:10.1186/1746-1596-9-61

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