Table 2

Characteristics of APOE ϵ2/ϵ3/ϵ4 polymorphism
Year Author Race Case/Controls (n) Genotypes (case/controls, n) Alleles (case/controls, n)
ϵ2/ϵ2 ϵ2/ϵ3 ϵ2/ϵ4 ϵ3/ϵ3 ϵ3/ϵ4 ϵ4/ϵ4 ϵ2 ϵ3 ϵ4
2003 Guerra A Caucasian 31/81 0/0 6/4 0/0 63/20 13/7 0/0 6/4 145/51 13/7
2008 Srivastava N Asian Indian 159/278 0/1 17/18 2/6 90/198 41/55 9/0 19/30 238/469 61/61
2010 Ergun MA Asian Chinese 38/42 0/2 2/0 12/4 8/9 16/26 0/1 14/8 34/44 28/32
2012 Zhang J Asian Chinese 282/172 1/3 46/16 7/2 186/123 40/27 2/1 55/24 458/289 51/31
2012 Zarkesh M Asian Iran 463/370 1/1 48/38 6/7 348/268 63/53 3/3 56/47 807/627 75/66
Module Case/Controls (n) Model selected Heterogeneity (I2)% P value OR (95% CI)
ϵ2/ϵ2/ϵ3/ϵ3 954/813 Fixed 0 0.12 0.35 (0.09-1.32)
ϵ2/ϵ3ϵ3/ϵ3 814/694 Fixed 48 0.07 1.33 (0.98-1.82)
ϵ2/ϵ4/ϵ3/ϵ3 695/618 Fixed 0 0.92 0.96 (0.45-2.05)
ϵ3/ϵ4/ϵ3/ϵ3 868/786 Fixed 28 0.7 1.05 (0.82-1.35)
ϵ4/ϵ4/ϵ3/ϵ3 695/618 Random 63 0.54 1.89 (0.25-14.46)
ϵ2/ϵ3 1832/1593 Fixed 23 0.26 1.16 (0.90-1.51)
ϵ4/ϵ3 1910/1681 Random 65 0.54 1.13 (0.77-1.66

Tang et al.

Tang et al. Diagnostic Pathology 2014 9:56   doi:10.1186/1746-1596-9-56

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