Table 1

Characteristics of 17 single nucleotide polymorphisms
Gene SNP Year Author Race Cases/Controls (n) Allele 1 Allele 2 Model selected Heterogeneity P value Odds ratio (95% confidence interval)
(Case/Controls, n) (Case/Controls, n) (I2)%
GNB3 rs5443 1999 Siffert W Caucasian 92/207 108/392 76/122 Fixed 42 0.47 1.04 (0.93-1.16)
(C/T) 1999 Siffert W Asian Chinese 186/832 166/886 206/778
1999 Siffert W African 127/607 34/219 220/995
2000 Siffert W Caucasian 207/92 292/108 122/76
2001 Hinney A Caucasian 491/330 695/442 287/218
2001 Benjafield AV Caucasian 92/188 133/284 51/92
2001 Ohshiro Y Asian Japanese 208/150 215/148 201/152
2004 Suwazono Y Asian Japanese 505/2120 517/2177 493/2063
2008 Wang X Asian Chinese 129/270 442/285 376/255
2013 Hsiao TJ Asian Chinese 467/505 402/441 532/569
MTHFR rs1801133 2007 Terruzzi I Caucasian 84/52 90/61 78/43 Fixed 0 0.59 1.05 (0.87-1.27)
(C/T) 2010 Tavakkoly Bazzaz J Asian Iranian 74/207 109/306 39/108
2012 Yin RX Asian Chinese 751/978 1049/1383 453/573
CNR1 rs806381 2008 Benzinou M Caucasian 839/1726 1163/2362 515/1090 Fixed 0 0.5 1.04 (0.93-1.17)
(A/G) 2008 Jaeger JP Caucasian 430/317 613/464 247/170
2012 Zhuang M Asian Chinese 1662/1070 2345/1550 979/590
BDNF rs6265 2005 Friedel S Caucasian 183/283 342/448 81/118 Fixed 46 0.8 1.01 (0.92-1.11)
(G/A) 2009 Hotta K Asian Japanese 1127/1733 1367/2013 887/1453
2009 Marti A Caucasian 155/147 242/226 68/68
2011 Xi B Asian Chinese 1229/1619 1095/1554 1363/1684
2011 Rouskas K Caucasian 510/469 826/732 194/206
2012 Skledar M Caucasian 74/226 111/374 37/78
FAAH rs324420 2005 Sipe JC Caucasian 1094/1594 1777/984 411/204 Random 79 0.54 0.94 (0.76-1.16)
(C/A) 2005 Sipe JC African 507/107 687/161 327/53
2005 Sipe JC Asian 271/94 471/148 71/40
2007 Jensen DP Caucasian 4190/2507 6817/3991 1563/1023
2008 Durand E Caucasian 1517/1320 2473/2104 561/536
2008 Papazoglou D Caucasian 158/121 265/209 51/33
2008 Moneletone P Caucasian 378/110 614/194 142/26
2010 Muller TD Caucasian 2818/2818 3027/4607 689/1029
ADRB1 rs1801253 2001 Rydén M Caucasian 141/157 206/214 76/100 Fixed 0 0.5 1.03 (0.94-1.14)
(C/G) 2004 Tafel J Caucasian 296/134 403/180 189/88
2007 Gjesing AP Caucasian 4575/3073 6781/4609 2369/1537
2008 Ohshiro Y Asian Japanese 180/132 284/215 76/49
SH2B1 rs7498665 2009 Hotta K Asian Japanese 1129/1735 1943/3003 315/467 Fixed 0 0.0004 1.21 (1.09-1.34)
(A/G) 2010 Shi J Asian Chinese 829/1859 1427/3317 231/401
2011 Beckers S Caucasian 1045/317 1223/401 867/223
2011 Rouskas K Caucasian 510/469 673/675 347/263
2012 Volckmar AL Caucasian 3139/424 3728/557 2550/311
PCSK1 rs6232 2009 Happé F Caucasian 3570/7933 6735/15028 405/838 Fixed 34 0.08 1.14 (0.97-1.12)
(A/G) 2011 Rouskas K Caucasian 510/469 969/882 51/56
2012 Villalobos-Comparán M South American Mexican 1018/1364 2005/2709 31/19
2013 Choquet H European American 263/547 485/1041 41/53
2013 Dušátková L Asian Czech 668/770 1255/1469 81/71
PCSK1 rs6235 2009 Happé F Caucasian 3559/7793 5164/11432 1954/4154 Fixed 0 0.26 1.04 (0.97-1.12)
(G/C) 2012 Villalobos-Comparán M South America Mexican 994/1336 1575/2156 413/516
2013 Choquet H European - American 263/547 368/793 158/301
2013 Choquet H African - American 453/251 740/432 166/70
2013 Dušátková L Asian Czech 670/772 996/1130 344/414
2014 Hsiao TJ Asian Chinese 290/175 406/229 174/121
NPY2R rs1047214 2006 Torekov SS Caucasian 939/4767 1026/5295 852/4239 Fixed 0 0.54 0.97 (0.88-1.07)
(T/C) 2007 Siddiq A Caucasian 953/1042 1048/1132 858/952
2007 Wang HJ Caucasian 184/183 189/169 179/197
2009 Zhang J Asian Chinese 705/1325 1171/2133 239/517
FAIM2 rs7138803 2009 Hotta K Asian Japanese 1125/1726 1408/2251 842/1201 Fixed 0 0.04 1.11 (1.01-1.22)
(G/A) 2011 Xi B Asian Chinese 1229/1619 1711/2332 747/906
2011 Rouskas K Caucasian 510/469 643/610 377/328
2013 Li C Asian Chinese 242/469 331/663 153/275
2013 Zhao XY Asian Chinese 371/393 534/565 208/221
SERPINE1 rs1799768 2001 Sartori MT Caucasian 93/79 95/84 91/74 Fixed 39 0.07 0.83 (0.67-1.02)
(4G/5G) 2002 Hoffstedt J Caucasian 317/188 305/141 329/235
2006 Berberoğlu M Asian Turk 126/133 151/133 101/133
2008 Solá E Caucasian 67/67 70/65 64/69
2008 Kinik ST Asian Turk 39/38 52/36 26/40
2011 Espino A South American Chilean 50/71 32/51 44/52
2012 Wingeyer SD South American Argentine 110/111 92/109 128/113
PON1 rs854560 2011 Veiga L Caucasian 81/74 101/90 61/58 Fixed 31 0.4 0.87 (0.62-1.21)
(A/T) 2011 Martínez-Salazar MF South American Mexican 63/64 114/101 12/27
2013 Rupérez AI Caucasian 177/81 210/219 137/143
PON1 rs662 2011 Veiga L Caucasian 81/74 68/44 94/104 Fixed 18 0.6 1.09 (0.79-1.51)
(G/A) 2011 Martínez-Salazar MF South American Mexican 63/64 66/65 60/63
2013 Rupérez AI Caucasian 177/81 252/249 102/111
CETP TaqIB 2006 Huang ZY Asian Chinese 199/141 243/162 155/120 Fixed 0 0.23 0.91 (0.79-1.06)
(B1/B2) 2008 Srivastava N Asian Indian 159/278 153/263 165/293
2010 Ruan X Asian Chinese 934/924 1104/1028 764/820
2011 Huang Y Asian Chinese 206/132 250/155 162/109
UCP1 rs1800592 1998 Gagnon J Caucasian 674/311 1013/473 335/149 Random 60 0.23 1.19 (0.90-1.57)
(A/G) 2000 Proenza AM Asian Turk 136/94 189/131 83/57
2002 Kieć-Wilk B Caucasian 12/106 18/146 6/66
2002 Nieters A Caucasian 154/153 232/231 76/75
2003 Forga Ll Caucasian 159/154 258/244 60/64
2004 Ramis JM Caucasian 82/170 259/433 49/81
2008 Mottagui-Tabar S Caucasian 91/479 433/736 149/222
2009 Shen ZN Asian Chinese 127/257 129/240 125/274
ABCA1 rs2230806 2006 Porchay I Caucasian 2097/2947 2992/4238 1202/1656 Fixed 0 0.87 1.01 (0.90-1.13)
(G/A) 2007 Kitjaroentham A Asian Thai 112/117 143/143 81/91
2011 Huang Y Asian Chinese 206/132 233/141 179/123

Tang et al.

Tang et al. Diagnostic Pathology 2014 9:56   doi:10.1186/1746-1596-9-56

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