Table 2

Statistics of the 24 dysregulated proteins in colorectal cancer compared with health individuals
Mass Colorectal cancer Health volunteer Regulation in colorectal cancer P-value
(Average ± SD) (Average ± SD)
1618.52※ 64.84 ± 37 20.91 ± 17.59 Up-regulation 0.001
1467.44※ 52 ± 36.99 12.41 ± 6.73 Up-regulation 0.000
4214.69※ 45.08 ± 24.84 100.83 ± 26.97 Down-regulation 0.000
798.20 41.9 ± 26.18 17.04 ± 6.00 Up-regulation 0.004
825.73 25.51 ± 16.96 11.25 ± 3.07 Up-regulation 0.007
651.55 16.05 ± 15.27 30.14 ± 14.65 Down-regulation 0.007
1656.22※ 13.77 ± 7.10 4.69 ± 2.63 Up-regulation 0.000
667.29 12.34 ± 9.65 19.76 ± 8.55 Down-regulation 0.028
1505.47※ 10.81 ± 5.89 3.86 ± 1.18 Up-regulation 0.000
1521.72 10.49 ± 4.50 5.20 ± 2.38 Up-regulation 0.002
1208.30※ 10.39 ± 4.48 4.27 ± 1.05 Up-regulation 0.001
1867.23 10.00 ± 6.35 17.64 ± 7.03 Down-regulation 0.018
1585.25 9.64 ± 3.93 5.51 ± 2.48 Up-regulation 0.004
4096.50 7.39 ± 4.77 14.26 ± 3.80 Down-regulation 0.005
1780.03 6.90 ± 5.09 11.21 ± 5.26 Down-regulation 0.019
7791.73 6.43 ± 6.97 13.01 ± 3.03 Down-regulation 0.014
4058.71 3.59 ± 2.73 15.02 ± 6.18 Down-regulation 0.000
4198.23 3.53 ± 2.77 7.44 ± 2.62 Down-regulation 0.003
4271.61 2.04 ± 1.71 4.64 ± 1.51 Down-regulation 0.000
4174.45 1.53 ± 1.25 2.63 ± 1.07 Down-regulation 0.021
4177.42 1.50 ± 1.25 2.51 ± 1.13 Down-regulation 0.026
4079.82 1.45 ± 1.04 2.49 ± 0.91 Down-regulation 0.014
4076.90 1.43 ± 1.04 2.57 ± 0.87 Down-regulation 0.007
3939.53 1.08 ± 0.51 1.88 ± 0.68 Down-regulation 0.005

※The peptide selected for model construction.

Peak area.

★P value calculated with the Wilcoxon test; values lower than 0.05 suggest statistical relevance.

Fan et al.

Fan et al. Diagnostic Pathology 2014 9:53   doi:10.1186/1746-1596-9-53

Open Data