Email updates

Keep up to date with the latest news and content from Diagnostic Pathology and BioMed Central.

Open Access Highly Accessed Open Badges Case Report

Dysplastic intestinal-type metaplasia of appendiceal endometriosis: a mimic of low grade appendiceal mucinous neoplasm

Andrew Mitchell1*, Pierre Dubé2 and Lucas Sideris2

Author Affiliations

1 Department of Anatomic Pathology and Cytology, Maisonneuve-Rosemont Hospital, Montreal, Quebec, Canada

2 Department of Surgery, Maisonneuve-Rosemont Hospital, Montreal, Quebec, Canada

For all author emails, please log on.

Diagnostic Pathology 2014, 9:39  doi:10.1186/1746-1596-9-39

Published: 21 February 2014


We report an example of dysplastic intestinal-type metaplasia involving endometriosis of the appendix in a 45 year old woman. One other example of this phenomenon has been reported. As it occurs within the muscular wall of the appendix, confusion with low grade appendiceal mucinous neoplasm (LAMN) may occur. Evidence supporting the metaplastic nature of the intestinal epithelium is offered. As the initial pathological diagnosis was of invasive cancer with perforation of the appendix treatment consisted of peritonectomy and hyperthermic intraperitoneal chemotherapy (HIPEC).

Virtual slides

The virtual slides for this article can be found here: webcite.

Appendix; Endometriosis; Intestinal; Metaplasia; Dysplasia