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Open Access Highly Accessed Case Report

Dysplastic intestinal-type metaplasia of appendiceal endometriosis: a mimic of low grade appendiceal mucinous neoplasm

Andrew Mitchell1*, Pierre Dubé2 and Lucas Sideris2

Author Affiliations

1 Department of Anatomic Pathology and Cytology, Maisonneuve-Rosemont Hospital, Montreal, Quebec, Canada

2 Department of Surgery, Maisonneuve-Rosemont Hospital, Montreal, Quebec, Canada

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Diagnostic Pathology 2014, 9:39  doi:10.1186/1746-1596-9-39

Published: 21 February 2014

Abstract

We report an example of dysplastic intestinal-type metaplasia involving endometriosis of the appendix in a 45 year old woman. One other example of this phenomenon has been reported. As it occurs within the muscular wall of the appendix, confusion with low grade appendiceal mucinous neoplasm (LAMN) may occur. Evidence supporting the metaplastic nature of the intestinal epithelium is offered. As the initial pathological diagnosis was of invasive cancer with perforation of the appendix treatment consisted of peritonectomy and hyperthermic intraperitoneal chemotherapy (HIPEC).

Virtual slides

The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1068246472111756 webcite.

Keywords:
Appendix; Endometriosis; Intestinal; Metaplasia; Dysplasia