Table 2

Specificities and sensitivities of “SM invasion-associated” pathologic factors and combinations of two and three factors
“SM invasion- related” pathologic factors Specificity (95% CI) Sensitivity (95% CI)
Single factors
Poorly differentiated tumor 94.3% (80.64 - 98.78) 36.7% (22.04 - 54.25)
Cribriform pattern 98.3% (85.71 - 99.82) 16.7% (7.42 - 33.3)
Papillary feature 94.8% (80.64 - 98.78) 23.3% (11.9 - 40.67)
IEND 93.1% (78.31 - 98.05) 40% (24.76 - 98.78)
Combinations of two factors
Poorly differentiated tumor + IEND 100% (88.58 - 100) 15% (6.38 - 31.38)
Papillary feature + IEND 100% (88.58 - 100) 11.7% (4.42 - 27.31)
Cribriform pattern + IEND 100% (88.58 - 100) 8.3% (2.66 - 23.24)
Cribriform pattern + papillary feature 100% (88.58 - 100) 6.7% (1.88 - 21.06)
Poorly differentiated tumor + papillary feature 100% (88.58 - 100) 5% (1.18 - 18.79)
Poorly differentiated tumor + cribriform pattern 98.3% (85.71 - 99.82)
Combinations of three factors
Cribriform pattern + papillary feature + poorly differentiated tumor 100% (88.58 - 100) 5% (1.18 - 18.79)
Cribriform pattern + IEND + poorly differentiated tumor 100% (88.58 - 100) 3.3% (0.6 - 11.08)

Abbreviations: IEND intraglandular eosinophilic necrotic debris.

Lee et al.

Lee et al. Diagnostic Pathology 2014 9:34   doi:10.1186/1746-1596-9-34

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