Microscopic examination of the intraductal fibroadenoma or intradutal phyllodes tumour of the breast. (A) Low power view showed that its polypoid parts were composed of leaf-like processes with a hypocellular and prominent myxoid stroma, protruding into cystic spaces, reminiscent of intracanalicular type fibroadenoma or benign phyllodes tumour features (H&E stains). Bar = 200 μm. (B) In some areas, there were foci of typical intracanalicular variant of fibroadenoma, in which duct lumens were compressed by the proliferating myxoid stroma (H&E stains). Bar = 200 μm. (C) On high-power view, those stromal cells showed no significant atypia, but the covering hyperplastic epithelial components were also bland-looking in two cell layers. Mitotic figures were very rarely seen (H&E stains). Bar = 200 μm. (D) In others, tiny foci of benign intraductal papilloma with characteristic delicate fibrovascular stalks were rarely seen (H&E stains). Bar = 100 μm.
Hayano et al. Diagnostic Pathology 2014 9:32 doi:10.1186/1746-1596-9-32