Table 5

Copy number variations of mtDNA in late-stage laryngeal cancer — univariate associations with clinicopathological characteristics
Characteristics Copy number <4.02 Copy number >5.42
OR* (95% CI) P OR* (95% CI) P
Male vs. Female 8.83 (0.74-105.58) 0.09 3.58 (0.46-28.17) 0.23
Age 0.99 (0.93-1.06) 0.76 0.97 (0.91-1.04) 0.37
Differentiation1 0.37 (0.08-1.81) 0.22 0.36 (0.07-1.84) 0.22
Tumor invasion2 1.05 (0.48-2.33) 0.90 0.78 (0.35-1.74) 0.54
LNM3 1.57 (0.48-5.12) 0.45 1.37 (0.41-4.56) 0.61
Smoking history4 0.78 (0.19-3.21) 0.73 0.49 (0.12-2.04) 0.33
Survival status5 0.64 (0.20-2.08) 0.45 1.05 (0.32-3.47) 0.94

*OR: odds ratio with 95% confidence interval; 1Differentiation (well or moderate; poor or undifferentiation); 2Tumor invasion (T1; T2; T3; T4); 3LNM (lymph node metastasis); 4Smoking history (at least 10 pack-years); 5Survival status (Alive vs. Dead); The cases with 4.02-5.42 mtDNA copies were used as reference.

Dang et al.

Dang et al. Diagnostic Pathology 2014 9:28   doi:10.1186/1746-1596-9-28

Open Data