Table 3

Copy number variations of mtDNA in laryngeal cancer — univariate associations with clinicopathological characteristics
Characteristics Copy number <4.02 Copy number >5.42
OR* (95% CI) P OR* (95% CI) P
Male vs. Female 2.73 (0.37-20.28) 0.33 1.89 (0.30-11.86) 0.50
Age 1.00 (0.96-1.05) 0.92 1.01 (0.97-1.05) 0.78
Differentiation1 1.02 (0.25-4.10) 0.98 0.64 (0.17-3.01) 0.64
Tumor invasion2 1.43 (0.92-2.25) 0.11 0.94 (0.60-1.46) 0.77
TNM stage3 1.53 (1.04-2.25) 0.03 1.04 (0.71-1.51) 0.84
LNM4 2.31 (0.90-5.95) 0.08 1.50 (0.58-3.89) 0.41
Smoking history5 0.46 (0.16-1.34) 0.16 0.29 (0.10-0.84) 0.02
Survival status6 0.81 (0.36-1.84) 0.61 0.79 (0.35-1.77) 0.56

*OR: odds ratio with 95% confidence interval; 1Differentiation (well or moderate; poor or undifferentiation); 2Tumor invasion (T1; T2; T3; T4); 3TNM stage (I; II; III; IV); 4LNM (lymph node metastasis); 5Smoking history (at least 10 pack-years); 6Survival status (Alive vs. Dead); The cases with 4.02-5.42 mtDNA copies were used as reference.

Dang et al.

Dang et al. Diagnostic Pathology 2014 9:28   doi:10.1186/1746-1596-9-28

Open Data