Table 1

Clinicopathological features and EGFR gene status of the 44 adrenocortical tumors
Malignant (n = 22) Benign (n = 22) p value
Age (yrs)
 Mean 43.4 47.4 0.364
 Range 2–75 34–69
Sex
 Males 13 9 0.228
 Females 9 13
Hormonal function
 Functioning 8 7 0.498
 Non-functioning 14 15
Tumor location
 Right 14 13 0.757
 Left 8 9
Tumor size (cm)
 Mean 12.3 2.9 <0.001*
 Range 3-24 0.8-5.5
Tumor weight (g)
 Mean 847.0 10.6 <0.001*
 Range 12-3250 1-42
EGFR copy number
 Positive 11 0 <0.001*,†
 Negative 11 22
EGFR IHC
 Positive 14 7 0.035*
 Negative 8 15

EGFR, epidermal growth factor receptor; IHC, immunohistochemistry.

*Statistically significant.

Fisher’s exact test (two-tailed).

Zhang et al.

Zhang et al. Diagnostic Pathology 2014 9:19   doi:10.1186/1746-1596-9-19

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