Table 2

Main results of pooled ORs in this meta-analysis
Study groups n Gln v Lys Gln/Gln v Lys/Lys Lys/Gln v Lys/Lys Lys/Gln + Gln/Gln v Lys/Lys Gln/Gln v Lys/Lys + Lys/Gln
OR (95% CI) Ph OR (95% CI) Ph OR (95% CI) Ph OR (95% CI) Ph OR (95% CI) Ph
All 18 1.05(0.95–1.18) <0.001 1.18(0.96–1.45) 0.030 1.02(0.90–1.17) 0.011 1.05(0.91–1.21) 0.001 1.11(0.98–1.26) 0.359
Ethnicity 18
 Caucasian 11 1.08(0.96–1.23) 0.002 1.17(0.92–1.49) 0.008 1.06(0.91–1.25) 0.033 1.09(0.92–1.29) 0.004 1.11(0.97–1.27) 0.150
 Asian 7 0.99(0.78–1.26) 0.026 1.13(0.75–1.70) 0.437 0.95(0.73–1.23) 0.062 0.97(0.74–1.27) 0.028 1.09(0.74–1.60) 0.687
Source
 HB 13 1.11(0.98–1.27) 0.001 1.26(0.98–1.61) 0.014 1.07(0.91–1.27) 0.009 1.11(0.93–1.33) 0.001 1.16(1.00–1.33) 0.273
 Mix 1 1.05(0.88–1.26) 1.08(0.74–1.57) 1.08(0.83–1.41) 1.08(0.85–1.38) 1.04(0.73–1.47)
 PB 3 0.86(0.62–1.19) 0.193 1.25(0.44–3.54) 0.870 0.82(0.57–1.18) 0.181 0.83(0.57–1.19) 0.168 1.26(0.45–3.57) 0.888
 nest 1 0.78(0.56–1.08) 0.54(0.26–1.16) 0.90(0.56–1.46) 0.80(0.51–1.27) 0.58 (0.28–1.17)
Cancer type 6 0.95(0.72–1.25) 0.005 0.88(0.65–1.18) 0.185 0.87(0.60–1.27) 0.007 0.90(0.61–1.31) 0.002 0.97(0.73–1.28) 0.640
 LC 2 0.72(0.48–1.10) 0.339 0.72(0.48–1.10) 0.383 0.66(0.48–0.91) 0.347 0.69(0.48–0.97) 0.285 0.93(0.64–1.34) 0.655
 OC 3 1.16(0.68–1.98) 0.007 1.08(0.69–1.69) 0.075 1.18(0.67–2.05) 0.036 1.20(0.65–2.21) 0.012 1.02(0.66–1.58) 0.213
 NPC 1 0.60(0.36–1.00) 0.97(0.06–15.66) 0.54(0.31–0.94) 0.55(0.32–0.95) 1.10(0.07–17.72)

Ph P-value of Q-test for heterogeneity test, HB hospital-based study, PB population-based study, nest nested case–control study, LC laryngeal cancer, OC oral cancer, NPC nasopharyngeal cancer.

Lin et al.

Lin et al. Diagnostic Pathology 2014 9:15   doi:10.1186/1746-1596-9-15

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