Table 2

Meta-analysis of the associations between CYP1B1 L432V polymorphism and urinary cancer risk
Cancer Number of studies Cases/controls Comparison Test of association Test of heterogeneity Publication bias
OR 95% CI P Value Q P Value I2(%) P Value (Begg’s)
Prostate 10 5949/5388 CC vs GG 0.942 0.868-1.022 0.151 20.23 0.017 55.5 0.917
CC vs CG 0.947 0.881-1.018 0.137 23.13 0.006 61.1 0.212
CC vs CG + GG 0.952 0.895-1.013 0.120 20.00 0.018 55.0 0.671
C vs G 0.963 0.920-1.008 0.108 24.36 0.004 63.0 0.723
Bladder 5 1658/1593 CC vs GG 1.061 0.962-1.171 0.234 2.23 1 0.0 0.035
CC vs CG 1.000 0.926-1.079 0.991 7.20 0.126 44.4 0.317
CC vs CG + GG 1.016 0.947-1.090 0.661 6.25 0.181 36.0 0.156
C vs G 1.026 0.977-1.077 0.312 3.75 0 0.0 0.060
Renal 2 337/408 CC vs GG 0.740 0.593-0.922 0.007 0.73 0.394 0 -
CC vs CG 0.816 0.686-0.969 0.021 1.34 0.248 25.2 -
CC vs CG + GG 0.787 0.673-0.922 0.003 1.35 0.245 26.0 -
C vs G 0.818 0.729-0.917 0.001 1.82 0.178 45 -
Overall 17 7944/7389 CC vs GG 0.941 0.876-1.012 0.103 35.2 0.004 54.6 0.607
CC vs CG 0.937 0.881-0.996 0.037 37.29 0.002 57.1 0.076
CC vs CG + GG 0.942 0.890-0.997 0.038 37.97 0.002 57.9 0.199
C vs G 0.957 0.917-0.998 0.039 46.07 0 65.3 0.302

Jiang et al.

Jiang et al. Diagnostic Pathology 2014 9:113   doi:10.1186/1746-1596-9-113

Open Data