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Open Access Case Report

Atypical esthesioneuroblastoma invading oral cavity: a case report and review of the literature

Sandra Ventorin von Zeidler1*, Rafaela Guidi2, Rita de Cássia Gonçalves Alencar3, Renato Aguiar3, Elismauro Francisco Mendonça4, Aline Carvalho Batista4 and Rejane Faria Ribeiro-Rotta4

Author Affiliations

1 Department of Pathology, Federal University of Espírito Santo, Piratininga n.180/602, Praia da Costa, Vila Velha – ES, 29101-220 Vitória, Brazil

2 Oral Health Division, State Health Department, Goiânia, Brazil

3 Association of Cancer Combat in Goiás, Araújo Jorge Hospital, Goiânia, Brazil

4 School of Dentistry, Federal University of Goiás, Goiânia, Brazil

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Diagnostic Pathology 2014, 9:10  doi:10.1186/1746-1596-9-10

Published: 20 January 2014

Abstract

Esthesioneuroblastoma is an uncommon tumour of neuroectodermal origin. The authors describe a rare presentation of an atypical esthesioneuroblastoma invading oral cavity. The clinical presentation, aetiology, diagnosis, and management of this condition are discussed. The patient developed significant swelling in the right anterosuperior alveolar mucosa and had moderate tooth mobility. Conventional x-rays and computed tomography revealed a large osteolytic lesion, with imprecise limits. Histological findings along with immunohistochemical staining results and clinical features led to the diagnosis of high-grade esthesioneuroblastoma. Local recurrences and neck metastasis were detected. The rare oral findings produced delayed in diagnosis which may lead to a compromise in planning and execution of further radical management and thus a poor prognosis.

Virtual slides

The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1168853011139286 webcite.

Keywords:
Esthesioneuroblastoma; Olfactory neuroblastoma; Maxillary neoplasms; Diagnosis; Oral cavity