Ground truth (Left) magnified 250 × 250 region of a frame and (right) the same region with the nuclei delineated by a pathologist. Nuclei delineated with a thinner outline are hard to distinguish from the background. Dark and bright areas can indiscriminately occur inside and outside nuclei.
Veillard et al. Diagnostic Pathology 2013 8(Suppl 1):S5 doi:10.1186/1746-1596-8-S1-S5