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This article is part of the supplement: Proceedings of the 11th European Congress on Telepathology and 5th International Congress on Virtual Microscopy

Open Access Proceedings

Quantitative phase imaging and Raman micro-spectroscopy applied to Malaria

Jacques Klossa1*, Benoit Wattelier2, Teddy Happillon3, Dominique Toubas34, Lucie de Laulanie2, Valérie Untereiner3, Pierre Bon2 and Michel Manfait1

Author Affiliations

1 TRIBVN, 39, rue Louveau, 92320 Châtillon, France

2 Phasics, Campus de l'Ecole Polytechnique, 91128 Palaiseau, France

3 MEDyC FRE/CNRS 3481, 51096 Reims, France

4 CHU de Reims, Laboratoire de parasitologie-mycologie, 51100 Reims, France

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Diagnostic Pathology 2013, 8(Suppl 1):S42  doi:10.1186/1746-1596-8-S1-S42

Published: 30 September 2013

First paragraph (this article has no abstract)

Malaria is due to parasitism of red blood cells (RBC) by protozoan parasites of the genus Plasmodium. Three main parameters have to be determined for patient treatment: parasite species, the rate of infected blood cells (parasitemia), and development stage. Even if a series of laboratory techniques are available, a suited treatment needs microscopy skills [1]. Microscopic observation needs a specialist and is time consuming (e.g. observation of hundreds fields of view at 100x immersion objective) and automating 100x slide scanning of white light imaging of thin film stained blood smears is not straightforward.