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This article is part of the supplement: Proceedings of the 11th European Congress on Telepathology and 5th International Congress on Virtual Microscopy

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Highlighting peritumoral areas in human skin cancer biopsies by infrared micro-spectroscopy

David Sebiskveradze1, Cyril Gobinet1*, Valeriu Vrabie2, Pierre Jeannesson1, Olivier Piot1 and Michel Manfait1

Author Affiliations

1 MéDIAN, CNRS FRE 3481 MEDyC, SFR Cap-Santé, Université de Reims Champagne-Ardenne, 51 rue Cognacq-Jay, 51096 Reims, France

2 CReSTIC, Université de Reims Champagne-Ardenne, Chaussée du Port, 51000 Châlons-en-Champagne, France

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Diagnostic Pathology 2013, 8(Suppl 1):S33  doi:10.1186/1746-1596-8-S1-S33

Published: 30 September 2013

First paragraph (this article has no abstract)

Fourier transform mid-infrared (FT–IR) microspectroscopy is a label-free optical method based on the interaction between an incident light beam and matter. This vibrational spectroscopy permits to probe the biochemical composition of the analyzed sample and thus gives information about the structure of this sample. Associated with an imaging system, FT–IR microspectroscopy of human tissues can be used as a very sensitive, non-destructive and non-subjective tool for the detection and localization of tumoral areas independently of visual morphology. Thus, FT–IR microimaging has demonstrated potential to provide clinically relevant diagnostic information in oncology [1-3].