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This article is part of the supplement: Proceedings of the 11th European Congress on Telepathology and 5th International Congress on Virtual Microscopy

Open Access Proceedings

A rich internet application for remote visualization and collaborative annotation of digital slides in histology and cytology

Raphaël Marée123*, Benjamin Stévens12, Loïc Rollus12, Natacha Rocks4, Xavier Moles Lopez56, Isabelle Salmon67, Didier Cataldo4 and Louis Wehenkel12

Author Affiliations

1 GIGA-Systems Biology & Chemical Biology, GIGA-R, University of Liège, Belgium

2 Systems and Modeling, Montefiore Institute, University of Liège, Belgium

3 GIGA Bioinformatics Core Facility, GIGA, University of Liège, Belgium

4 Laboratory of Tumor & Development Biology, GIGA-Cancer, University of Liège, Belgium

5 Laboratory of Image Synthesis and Analysis (LISA), Faculty of Applied Sciences, ULB, Brussels, Belgium

6 DIAPATH, Center for Microscopy and Molecular Imaging (CMMI), Gosselies, Belgium

7 Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles, Belgium

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Diagnostic Pathology 2013, 8(Suppl 1):S26  doi:10.1186/1746-1596-8-S1-S26

Published: 30 September 2013

First paragraph (this article has no abstract)

In the field of digital pathology and biomedical research, there is a strong need for efficient tools to build pathology atlases and to foster collaboration between researchers, pathologists (e.g. for inter-observer concordance studies) and computer scientists (e.g. for development and extensive validation of novel computer vision algorithms). Although many efforts have been made in virtual microscopy and telepathology in the recent years [1-4] , many of the resulting frameworks are not fully web-based therefore limiting collaboration, or they are vendor-dependant therefore limited in terms of supported image formats, or they use proprietary modules that prevent cross-browser compatibility and seamless execution on mobile devices, or they have restricted functionalities (e.g. images can only be annotated manually with image-level tags or fixed markers), or their design limits their application domain (e.g. education only, or disease-specific). In this paper, we present a general-purpose, rich internet application using recent web technologies and integrating various open-source tools, standards and generic algorithms for remote visualization and collaborative annotation of digital slides.