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This article is part of the supplement: Proceedings of the 11th European Congress on Telepathology and 5th International Congress on Virtual Microscopy

Open Access Proceedings

A morphometric tool applied to angiogenesis research based on vessel segmentation

Maria-Milagro Fernández-Carrobles1, Irene Tadeo2, Rosa Noguera3, Marcial García-Rojo4, Oscar Déniz1, Jesús Salido1 and Gloria Bueno1*

Author affiliations

1 VISILAB, Universidad de Castilla-La Mancha, Spain

2 Fundación Investigación Clínico de Valencia-Instituto de Investigación Sanitaria INCLIVA, Spain

3 Laboratorio de Patología Molecular, Dpto. de Patología, Fac. de Medicina y Odontología, Universidad de Valencia, Spain

4 Dpto. Anatomía Patológica, Hospital General Universitario de Ciudad Real, Spain

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Citation and License

Diagnostic Pathology 2013, 8(Suppl 1):S20  doi:10.1186/1746-1596-8-S1-S20

Published: 30 September 2013

First paragraph (this article has no abstract)

It is now widely accepted that tumor growth and metastasis are angiogenesis and lymphangiogenesis-dependent providing novel therapeutic targets in malignant disease [1-3]. A common feature of the tumor vessels studies is that the investigators focus on microvessel density overlooking other parameters that might be significant, such as the size and shape of the microvessels [4]. In many aspects, tumor vessels are different from normal vessels [5,6]. Studies have revealed the importance of the size and shape of blood vessels in, for example laryngeal tumors [7].