A): The set of dynamic particulae resembling a Gibbs cloud-point obtained expressing as vector magnitudes the normalised log value of CK7+ areas and the normalised log value of fibrosis in our patients. B) The points are transferred to the oriented line of real numbers representing the standardised trajectory of the process. C) An ogival cumulative curve orders the dynamic particula within the three clouds in panel A. This curve is sub-divided into three tertiles marked by blue points and represents the trajectory of the overall dynamic process of PBC from α to ω.
Dioguardi et al. Diagnostic Pathology 2013 8(Suppl 1):S16 doi:10.1186/1746-1596-8-S1-S16