A: Necrotic focus is accompanied by nuclear pseudopalisading in MPNST, 2B: Neoplastic cells with cytoplasm and round nuclei are arranged in a cordlike pattern, 2C: The neoplastic cells show diffuse expression of S-100. IHC, 2D: The neoplastic cells show strong expression of vimentin. IHC 2E: A number of neoplastic cells show a marked cytoplasmic and nuclear immunoreaction for S-100 protein 2F: Fusiform or spindle-shaped neoplasmic cells are arranged in interdacing fascicles.
Tavasoly et al. Diagnostic Pathology 2013 8:86 doi:10.1186/1746-1596-8-86