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Open Access Open Badges Research

Clinico- pathological profile of patients with breast diseases

Hafiz Muhammad Aslam1, Shafaq Saleem1, Hiba Arshad Shaikh1, Nazish Shahid1, Anum Mughal1 and Ribak Umah2*

Author Affiliations

1 Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan

2 Dakshin Dinajpur District, West Bengal, Bangladesh

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Diagnostic Pathology 2013, 8:77  doi:10.1186/1746-1596-8-77

Published: 9 May 2013



To evaluate the spectrum of breast diseases and their association with presenting complains of patients.


It was a cross sectional study conducted from 1st January 2010 – 30th December 2012. A total of 254 breast specimens of patients, who were admitted in Civil Hospital Karachi with breast complaints, were included. Specimens were collected either from mastectomy, lumpectomy or needle biopsy from the admitted patients. Informed written consent was taken from all the patients. All patients with primary breast diseases were included. Patients undergoing chemotherapy or with secondary breast disease and slides with insufficient specimen were excluded. All data was entered and analyzed through SPSS 19.


There were 254 breast lesions, histologically diagnosed in 3 year review period. The overall mean age of patients with breast lesion was 25.18, SD ± 11.73 with a wide age range of 12–74 years. Most common cases identified are benign 191(75.3%), followed by inflammatory 30(11.8%) and malignant lesions 30(11.8%). Most patients presenting with the complain of pain have diagnosis of fibroadenoma 24 (63.2%) while patient with complain of lump also have the most common diagnosis of fibroadenoma 147 (72.8%).


Study shows that in Pakistani females, mostly encountered breast lesion was fibroadenoma. Due to lack of awareness breast diseases present lately. Awareness must be created among women to reduce the mortality and morbidity with breast lesions.

Virtual slides

The virtual slide(s) for this article can be found here: webcite.

Breast diseases; Benign breast diseases; Fibroadenoma