Cytomorphologic examination of the fine needle aspiration cytology in PC specimens. (A) The cytology specimens were consisted predominantly of many individual, scattered malignant giant bizarre cells having often multi-nucleated pleomorphic nuclei in a hemorrhagic or inflammatory background (Papanicolaou stains). Bar = 100 μm. (B) A small number of clusters of cohesive and sheet-like or three-dimensional malignant tumor cells coexisted. Those malignant cells showed very large (up to approximately 100 μm in diameter), pleomorphic, and bizarre or spindle nuclei and had relatively abundant cytoplasm. Additionally, the nuclei contained conspicuous nucleoli and numerous mitotic figures including atypical mitoses (arrows) (Papanicolaou stains). Bar = 100 μm.
Yamada et al. Diagnostic Pathology 2013 8:75 doi:10.1186/1746-1596-8-75