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Open Access Case Report

Hydroa vacciniforme-like lymphoma of an adult: a case report with review of the literature

Mi Wang1, Sheng Wang1, Qun-Pei Yang2, Yan-Mei Liu2, Li-Min Gao2, Hong Sun2 and Wei-Ping Liu2*

Author affiliations

1 Department of Dermatovenerology, West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, China

2 Department of Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, China

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Citation and License

Diagnostic Pathology 2013, 8:72  doi:10.1186/1746-1596-8-72

Published: 1 May 2013

Abstract

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The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/7644172219178472 webcite

Hydroa vacciniforme-like lymphoma (HVL) is a rare type of Epstein-Barr virus (EBV)-positive lymphoma of cytotoxic T-cell or natural killer cell origin that mainly affect children, characterized by a vesicopapular skin eruption that clinically resemble hydroa vacciniforme (HV). In current study, we report an adult patient with the tumor. The patient presented similar morphologic, immunophenotypic and genotypic changes of the disease with that occurred in children, whereas clinically, he showed a prolonged clinical course without hepatosplenomegaly or generalized lymphadenopathy. Whether there are some differences in biologic behavior between children and adults still remains unknown and it is necessary to collect more data to observe and to investigate in the future.

Keywords:
Hydroa vacciniforme-like lymphoma; Epstein-Barr virus; Adult