Quantitative analysis of Treg cells and Th17 cells in the peripheral blood of three groups. Peripheral blood samples were collected from 65 cases of cervical cancer patients, 42 cases of cervical CIN patients and 40 cases of healthy people. Quantitative results of the flow cytometric analysis were shown. (A) Percentages of CD4+CD25+Treg cells in CD4+T cells; (B) Percentages of CD4+CD25+CD127lowTreg cells in CD4+T cells; (C) Percentages of CD8+CD25+CD127lowTreg cells in CD8+T cells; (D) Percentages of CD4+CD25+ FOXP3+Treg cells in CD4+T cells; (E) Percentages of CD4+CD25-FOXP3+Treg in CD4+T cells; (F) Percentages of CD8+CD25+ FOXP3+Treg cells in CD8+T cells; (G) Percentages of CD4+IL-17+Th17 cells in CD4+T cells. (H) Ratio of Th17/ Treg in three groups. Each experiment was performed three times. Percentages of cells in the UCC group and the cervical group were compared with those in the healthy control group. *p < 0.05.
Chen et al. Diagnostic Pathology 2013 8:61 doi:10.1186/1746-1596-8-61