Table 3

Literature data on sodium and chloride concentrations in saliva of patients with cystic fibrosis (CF)
Researchers Date CFG° CG* Method Results
Chernick et al. [13] 1961 12 12 Flame photometry/titration High level of potassium and low levels of sodium and chloride in patients with CF
Marmar et al. [14] 1966 12 13 Flame photometry/titration High levels of sodium and chloride in CF patients
Lawson et al. [15] 1967 5 50 Electrode selective High level of sodium in CF patients
Wiesmann et al. [16] 1970 23 12 Atomic absorption spectrophotometry No significant differences in sodium level
Fritz et al. [17] 1972 11 0 Unquoted High levels of chloride and sodium for saliva flow in CF patients
Blomfield et al. [18] 1973 35 28 Atomic absorption spectrophotometry High levels of chloride and sodium in CF patients
Kollberg et al. [19] 1982 9 11 Flame-emission photometry High level of sodium in CF patients
Jimenez-Reyes & Sanches-Aguirre [20] 1996 9 9 Atomic absorption spectrophotometry High level of sodium in CF patients

°CFG: cystic fibrosis group; *CG: control group. Databases of Pubmed, Scielo, Medline and HighWire Stanford University, in the period of 1951 to 2011 were searched. The keywords were: biochemical parameters of saliva and cystic fibrosis.

Gonçalves et al.

Gonçalves et al. Diagnostic Pathology 2013 8:46   doi:10.1186/1746-1596-8-46

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