Table 1

Comparison of volume, pH and biochemical parameters of saliva in cystic fibrosis patients and healthy controls
Parameter CF patients (n=80) Healthy subjects (n=84) p-value*** p-value corrected by Bonferroni test
Mean ± SD (95% CI) Median Mean ± SD (95% CI) Median
Calcium* 2.03± 0.99 (0.30 – 4.65) 1.85 2.15 ± 2.79 (0.71 – 23) 1.61 0.114 1
Glucose* 13.02 ± 18.69 (3 – 147) 8 9.25± 3.56 (3 – 20) 9.5 0.932 1
Lactate* 0.91 ± 0,89 (0.2 – 5.6) 0.7 0.81± 0.74 (0.1 – 4.3) 0.6 0.463 1
Chloride* 27.82 ± 13.47 (12 – 89) 26 18.04 ± 8.3 (8 – 43) 16 <0.001 <0.009
Volume** 0.63 ± 0.3 (0.1– 1.5) 0.6 0.8 ± 0.5 (0 – 2) 1 <0.001 <0.009
Ph 6.86 ± 0.45 (6.27 – 7.8) 6.83 7.17 ± 0,44 (6.3 – 7.85) 7.2 <0.001 <0.009
Potassium* 19.66± 3.25 (10.8 – 24.8) 19.55 16.82 ± 3.22 (6.5 -24) 17.20 <0.001 <0.009
Sodium* 19.90 ± 9.3 (8 – 48) 17.5 12.26 ± 4.31 (7 – 29) 11 <0.001 <0.009
Bicarbonate* 5.53 ± 3.98 (0 – 22) 3 3.58 ± 3.98 (0 -16) 1.95 0.051 0.459

CF – Cystic Fibrosis, CI – Confidential interval, n – number of patients, SD – Standard Deviation.

* mmol/L.

** N for volume is 68 in CF patients and 64 in healthy subjects, unlike the other parameters.

*** The Statistical analyses were performed by Mann-Whitney test. The positive p-value is in bold.

Gonçalves et al.

Gonçalves et al. Diagnostic Pathology 2013 8:46   doi:10.1186/1746-1596-8-46

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