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A rare primary tumor of the thyroid gland: report a new case of leiomyosarcoma and literature review

Bennani Amal*, Hinde El Fatemi, Ihsane Souaf, Kaouthar Moumna and Amarti Affaf

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Departement of pathology, Hassan II University Hospital, Fez 30000, Morocco

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Diagnostic Pathology 2013, 8:36  doi:10.1186/1746-1596-8-36

Published: 27 February 2013


Primary leiomyosarcomas of the thyroid gland are extremely rare. we report a case of a 72 year-old women with a painful growing mass of the left neck with skin fistula. The patient underwent a lobectomy. The tumor histology showed spindle-shaped cells arranged in interlacing fascicles that expressed desmine and Hcaldesmone, but were negative for cytokeratins and thyroglobulin. Total body CT scan didnt show any other tumor. The patient died two months after surgery. Primary thyroid leiomyosarcoma may be mistaken for other tumors, such as anaplastic or medullary carcinomas. Therefore, the diagnosis is difficult and requires numerous clinical, radiological, and pathological investigations.

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Primary leiomyosarcoma; Thyroid gland; Anaplastic carcinoma; Medullary carcinoma