Table 2

Association of CD44 and CD24 with clinicopathological variables in 69 SGMN patients
CD44 CD24
+ - p + - p
Gender Male 19 (13.0%) 9 (13.0%) 0.330 6 (8.7%) 22 (31.9%) 0.330
Female 31 (44.9%) 10 (14.5%) 12 (17.4%) 29 (42.0%)
Age ≤ 60 30 (43.5%) 11 (15.9%) 0.543 10 (14.5%) 31 (44.9%) 0.453
> 60 20 (29.0%) 8 (11.6%) 8 (11.6%) 20 (29.0%)
Smoking intake Yes 15 (21.7%) 8 (11.6%) 0.250 5 (7.2%) 18 (26.1%) 0.392
No 35 (50.7%) 11 (15.9%) 13 (18.8%) 33 (47.8%)
Alcohol intake Yes 9 (13.0%) 5 (7.2%) 0.324 5 (7.2%) 9 (13.0%) 0.275
No 41 (59.4%) 14 (20.3%) 13 (18.8%) 42 (60.9%)
PLSa Majorb 34 (49.3%) 8 (11.6%) 0.046 11 (15.9%) 31 (44.9%) 0.605
Minorc 16 (23.2%) 11 (15.9%) 7 (10.1%) 20 (29.0%)
Tumor size T1/T2 28 (40.6%) 14 (20.3%) 0.142 7 (10.1%) 35 (50.7%) 0.027
T3/T4 22 (31.9%) 5 (7.2%) 11 (15.9%) 16 (23.2%)
Clinical Stage I / II 19 (27.5%) 6 (8.7%) 0.419 2 (2.9%) 23 (33.3%) 0.008
III / VI 31 (44.9%) 13 (18.8%) 16 (23.2%) 28 (40.6%)
Treatment Surgery 14 (20.3%) 5 (7.2%) 0.572 4 (5.8%) 15 (21.7%) 0.398
Sur. Adj. T.d 36 (52.2%) 14 (20.3%) 14 (20.3%) 36 (52.2%)
Metastasis No 32 (46.4%) 11 (15.9%) 0.421 10 (14.5%) 33 (47.8%) 0.339
Yes 18 (26.1%) 8 (11.6%) 8 (11.6%) 18 (26.1%)
loco-regional No 33 (47.8%) 12 (17.4%) 0.519 10 (14.5%) 35 (50.7%) 0.236
recurrence Yes 17 (24.6%) 7 (10.1%) 8 (11.6%) 16 (23.2%)
Lymph node Negative 43 (62.3%) 15 (21.7%) 0.352 10 (14.5%) 48 (69.6%) 0.001
Positive 7 (10.1%) 4 (5.8%) 8 (11.6%) 3 (4.3%)
Death No 36 (52.2%) 12 (17.4%) 0.332 14 (20.3%) 34 (49.3%) 0.285
Yes 14 (20.3%) 7 (10.1%) 4 (5.8%) 17 (24.6%)
CD24 Negative 36 (52.2%) 15 (21.7%) 0.398
Positive 14 (20.3%) 4 (5.8%)
CD44 Negative 4 (5.8%) 15 (21.7%) 0.398
Positive 14 (20.3%) 36 (52.2%)

aPLS: Primary Lesion Site; bMajor: Major Salivary Glands (Parotid Gland/Submandibular Gland/Sublingual Gland); cMinor; Minor Salivary Glands; dSur. Adj. T.: Surgery with adjuvant therapy. Statistically significant difference (<0.05) by Fisher’s exact test (two variables) or χ2 (three or more variables) tests.

Soave et al.

Soave et al. Diagnostic Pathology 2013 8:29   doi:10.1186/1746-1596-8-29

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