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Open Access Case Report

Sertoliform cystadenoma: a rare benign tumour of the rete testis

Felix Bremmer1*, Stefan Schweyer3, Carl Ludwig Behnes1, Manfred Blech2 and Heinz Joachim Radzun1

Author Affiliations

1 Department of Pathology, University of Göttingen, Göttingen, Germany

2 Department of Urology, Helios Albert Schweitzer Hospital, Northeim, Germany

3 Gemeinschaftspraxis Pathologie, Starnberg, Germany

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Diagnostic Pathology 2013, 8:23  doi:10.1186/1746-1596-8-23

Published: 14 February 2013

Abstract

Sertoliform cystadenoma of the rete testis represents an uncommon benign tumour. They appear in patients from 26 to 62 years of age. We describe a case of a 66-year-old man with a tumour in the area of the epididymal head. The tumour markers were not increased. Under the assumption of a malignant testicular tumour an inguinal orchiectomy was performed. The cut surface of this tumour was of grey/white color and showed small cysts. The tumour consisted of two compartments. The epithelial like tumour cells showed a sertoliform growth pattern and cystic dilatations. In between the tumour cells repeatedly actin expressing sclerotic areas could be recognized as the second tumour component. Proliferative activity was not increased. Immunohistochemically the tumour cells were positiv for inhibin, S-100, and CD 99. Alpha feto protein (AFP), human chorionic gonadotropin (ß-HCG) and placental alkaline phosphatase (PLAP) as well as synaptophysin, epithelial membrane antigene (EMA), and BCL-2 were not expressed. As far as we know this is the sixth reported case of this tumour. Because of the benign nature of this tumour the correct diagnosis is important for the intra- and postoperative management. Here we present a case of this rare tumour and discuss potential differential diagnosis.

The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1956026143857335 webcite