Figure 1.

Immunohistochemical staining of Fascin in sciatic nerves of EAN rats. In normal rat sciatic nerves, Fascin expression was only occasionally observed in single cells (A). At day 7, the Fascin+ cells were observed clearly (B). Significant accumulation of Fascin+ cells could be observed at day 11 (C), maximal accumulation of Fascin+ cells in sciatic nerves was found at day 15 (D). From day 17, the accumulation of Fascin+ cells began to decrease (E), but finally the cellular accumulation returned to a control level by day 22 (F). Double staining experiments revealed that few Fascin+ cells co-expressed cd-3 (blue) representing T cells (G), and few Fascin+ cells co-expressed active macrophage marker ED1 (blue)at day 15 (H). Scale bars are 25 mm for all pictures.

Yang et al. Diagnostic Pathology 2013 8:213   doi:10.1186/1746-1596-8-213
Download authors' original image