Table 2

Immunohistochemical staining results of p53, MAPK, topoIIα and Ki67 expression in OSCs
Low-grade High-grade P
(n = 11) (n = 70)
p53, n (%)
negative 11 (100) 10 (14.3) < 0.001
positive 0 (0) 60 (85.7)
MAPK, n (%)
negative 4 (36.4) 58 (82.9) 0.003
positive 7 (63.6) 12 (17.1)
topoII alpha, n (%)
negative 7 (63.6) 13 (18.6) 0.001
positive 4 (36.4) 57 (81.4)
Ki67, median (min-max) 19 (7–54) 56.5 (18–98) < 0.001*

Based on χ2 test.

*Based on Mann–Whitney U test.

Sundov et al.

Sundov et al. Diagnostic Pathology 2013 8:21   doi:10.1186/1746-1596-8-21

Open Data