Figure 3.

Cytoplasmic (a-e) and nuclear (a, c and e) expression of PRMT5 is seen throughout the entire spectrum of lung tumors; representative examples of adenocarcinoma (a), squamous cell carcinoma (b-c), large cell neuroendocrine carcinoma (d) and typical carcinoid tumor (e); no PRMT5 is observed in normal alveolar parenchyma (f) Panels (b) and (d) illustrate low and high cytoplasmic expression, respectively; panels (a) and (e) illustrate low and high nuclear expression, respectively; immunohistochemistry; original magnification ×400.

Shilo et al. Diagnostic Pathology 2013 8:201   doi:10.1186/1746-1596-8-201
Download authors' original image