Photomicrographs of the cutaneous lesions. (A) Under low-power microscopic examination, the ulcerated lesion showed erosion of epidermis and diffuse infiltrating of large tumor cells in dermis and subcutaneous tissue. (B) The nodular cutaneous lesion was characterized by sheets of tumor cells in the dermis but the epidermotropism was not appreciated in the lesion. (C) Tumor cells were large epithelioid with large oval to convoluted nuclei and nuclear groves. (D) At high-power fields, the tumor cells exhibited significantly malignant cytological features with ill-defined cell borders and active mitotic figure (A and B, HE staining with original magnification ×40; C, HE staining with original magnification ×200; D, HE staining with original magnification ×400).
Li et al. Diagnostic Pathology 2013 8:20 doi:10.1186/1746-1596-8-20