Table 5

Correlation of EDNRB mRNA expression and clinicopathological parameters of colorectal cancer samples*
EDNRB expression relative to GAPDH
Characteristics n Mean SD SE p value
Gender Male 28 0.336 1.073 0.202 0.722
Female 14 0.250 0.480 0.130
Age (year) ≤60 16 0.221 0.444 0.111 0.836
>60 26 0.360 1.114 0.218
Stage 1/2 21 0.143 0.233 0.051 0.792
3/4 21 0.472 1.257 0.281
Lymph metastasis Yes 21 0.457 1.266 0.276 0.95
No 21 0.158 0.238 0.052
Distant metastasis Yes 8 0.781 1.996 0.706 0.741
No 34 0.196 0.351 0.060
CEA ≥5.0 ng/ml 15 0.121 0.156 0.040 0.723
<5.0 ng/ml 27 0.411 1.127 0.217
CA19-9 ≥37U/ml 9 0.102 0.153 0.051 0.526
<37U/ml 33 0.364 1.023 0.178
Tumor location Colon 26 0.428 1.145 0.225 0.351
Rectum 16 0.112 0.156 0.039
Differentiation Poor 10 0.719 1.779 0.558 0.494
Moderate 32 0.179 0.341 0.062
Well 0 / / /
Tumor size <5 cm 28 0.386 1.102 0.208 0.968
≥5 cm 14 0.151 0.248 0.066
Histological classification Adenocarcinoma 40 0.315 0.935 0.148 0.455
Mucinous adenocarcinoma 2 0.162 0.157 0.111
Undifferentiated carcinoma 0 / / /

*: SD denotes standard deviation and SE denotes standard error.

Chen et al.

Chen et al. Diagnostic Pathology 2013 8:199   doi:10.1186/1746-1596-8-199

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