Table 3

Association between the EDNRB methylation in CRC serum and clinicopathologicalfeatures
EDNRB Methylation
Characteristics n M U χ2 p value
Gender Male 28 27 1 0.404 0.525
Female 14 12 2
Age(year) ≤60 16 16 0 0.629 0.428
>60 26 23 3
Stage 1/2 21 18 3 1.436 0.231
3/4 21 21 0
Lymph metastasis Yes 21 21 0 1.436 0.231
No 21 18 3
Distant metastasis Yes 8 8 0 0.012 0.913
No 34 31 3
CEA ≥5.0 ng/ml 15 14 1 <0.001 1
<5.0 ng/ml 27 25 2
CA19-9 ≥37U/ml 9 8 1 <0.001 1
<37U/ml 33 31 2
Tumor location Colon 26 24 2 <0.001 1
Rectum 16 15 1
Differentiation Poor 10 10 0 0.091 0.763
Moderate 32 29 3
Well 0 0 0
Tumor size <5 cm 28 25 3 0.404 0.525
≥5 cm 14 14 0
Histological classification Adenocarcinoma 40 37 3 <0.001 1
Mucinous adenocarcinoma 2 2 0
Undifferentiated carcinoma 0 0 0

Chen et al.

Chen et al. Diagnostic Pathology 2013 8:199   doi:10.1186/1746-1596-8-199

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