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Open Access Case Report

Large cell neuroendocrine carcinoma (LCNEC) of the urinary bladder: a case report

Cristina Colarossi1, Piero Pino2, Dario Giuffrida3, Eleonora Aiello1, Rosario Costanzo1, Daniela Martinetti4 and Lorenzo Memeo1*

Author Affiliations

1 Pathology Unit, Department of Experimental Oncology, Mediterranean Institute of Oncology, Via Penninazzo 7, Viagrande, (CT), Italy

2 Urological Surgery Unit, Department of Experimental Oncology, Mediterranean Institute of Oncology, Via Penninazzo 7, Viagrande, (CT), Italy

3 Oncology Unit, Department of Experimental Oncology, Mediterranean Institute of Oncology, Via Penninazzo 7, Viagrande, (CT), Italy

4 IOM Ricerca Srl, Via Penninazzo 11, Viagrande, (CT), Italy

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Diagnostic Pathology 2013, 8:19  doi:10.1186/1746-1596-8-19

Published: 4 February 2013

Abstract

Neuroendocrine carcinoma of the urinary bladder is a rare entity, accounting less then 1% of urinary bladder malignancies. The vast majority of the neuroendocrine carcinoma of the urinary bladder is represented by small cell neuroendocrine carcinoma while just few cases of large cell neuroendocrine carcinoma (LCNEC) have been reported. In this cases report we describe a rare case of primary bladder LCNEC.

Virtual Slides

The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2474700528951562. webcite