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Recurrent cutaneous necrotizing eosinophilic vasculitis: a case report and review of the literature

Wenfei Li13, Wang Cao3, Haiyan Song1, Yanxia Ciu1, Xianmei Lu12* and Furen Zhang12

Author Affiliations

1 Shandong Provincial Hospital for Skin Diseases, Shandong University, Jinan 250022, China

2 Shandong Provincial Institute of Dermatology and Venereology, Jinan 250022, China

3 Department of Dermatology, Qianfoshan Hospital, Shandong University, Jinan 250014, China

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Diagnostic Pathology 2013, 8:185  doi:10.1186/1746-1596-8-185

Published: 7 November 2013


We report a case of recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) in a 57-year-old male. The patient presented with papules and pruritus of the lower limbs of more than 1 month duration, and with angioedema and intensively pruritic, necrotizing lesions of the bilateral anterior tibias and feet for 2 weeks. Treatment with systemic corticosteroids was administered for 1 month, and resulted in a significant improvement. We also present a review of the pertinent literature and discuss the clinical features, histopathological features, and differentiation of RCNEV.

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Vasculitis; eosinophilic; Recurrent; Ctaneous necrotizing; Corticosteroid