LLC in association with EBV. (a.) Loupe view of LLC. Note the well-circumscribed and expansive growth pattern with pushing borders (HE Stain, Magnification 2.5X). (b.) Microscopic view of LLC (HE Stain, Magnification 40X). (c.) EBER in situ hybridization in LLC (EBV-ISH, Magnification 40X). (d.) P53 positivity in the tumor cells (Magnification 40X). (e.) Retention of expression of the mismatch repair protein MLH1 and MSH6 (f.) (Magnification 40X).
Bittar et al. Diagnostic Pathology 2013 8:184 doi:10.1186/1746-1596-8-184