Table 1

Correlation of SOX9 expression with clinicopathological features of osteosarcoma
Clinicopathological features No.of cases SOX9 expression P
High(n, %) Low(n, %)
Age
<55 72 50 (69.4) 22 (30.6) NS
≥55 94 70 (74.5) 24 (25.5)
Gender
Male 96 70 (72.9) 26 (27.1) NS
Female 70 50 (71.4) 20 (28.6)
Tumor size(cm)
>8 88 62 (70.5) 26 (29.5) NS
≤8 78 58 (74.4) 20 (25.6)
Anatomic location
Tibia/femur 103 76 (73.8) 27 (26.2) NS
Elsewhere 63 44 (69.8) 19 (30.2)
Serum level of lactate dehydrogenase
Elevated 90 70 (77.8) 20 (22.2) NS
Normal 76 50 (65.8) 26 (34.2)
Serum level of alkaline phosphatase
Elevated 108 80 (74.1) 28 (25.9) NS
Normal 58 40 (69.1) 18 (30.9)
Clinical stage
IIA 68 32 (47.1) 36 (52.9) 0.02
IIB/III 98 88 (89.8) 10 (10.2)
Distant metastasis
Absent 124 78 (62.9) 46 (37.1) 0.008
Present 42 42 (100.0) 0 (0)
Response to chemotherapy
Good 68 32 (47.1) 36 (52.9) 0.02
Poor 98 88 (89.8) 10 (10.2)

Zhu et al.

Zhu et al. Diagnostic Pathology 2013 8:183   doi:10.1186/1746-1596-8-183

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