BGC-823 cell apoptosis and xenograft tumor experiment. A. Astragalus saponins induced apoptosis in BGC-823 cells. Cell apoptosis was analyzed by flow cytometry. Statistically significant (*p < 0.05)increases in annexin V + apoptotic cells were observed in Astragalus saponins–treated BGC-823 cells compared to controls. Data are presented as the mean of triplicate experiments. B. BGC-823 cell xenograft tumor experiment. Injection of Astragalus saponins inhibited tumor growth in a BGC-823 xenograft model compared with the blank control group. *Significant difference (p < 0.05).
Wang et al. Diagnostic Pathology 2013 8:179 doi:10.1186/1746-1596-8-179