Table 3

Copy number variations of mtDNA in gastric cancer — univariate associations with clinicopathological characteristics
Characteristics      Copy number <3.61      Copy number >5.35
OR* (95% CI) P OR* (95% CI) P
Male vs. Female 1.55 (0.42-5.70) 0.51 1.75 (0.37-8.30) 0.48
Age1 1.00 (0.65-1.52) 0.98 1.10 (0.67-1.79) 0.71
Tumor localization2 1.11 (0.51-2.42) 0.80 1.22 (0.50-2.99) 0.66
Tumor size3 1.31 (0.66-2.60) 0.45 1.37 (0.63-3.01) 0.43
Differentiation4 1.78 (0.58-5.49) 0.32 1.11 (0.31-4.04) 0.87
Tumor invasion5 0.82 (0.46-1.47) 0.50 0.69 (0.36-1.34) 0.27
TNM stage6 0.84 (0.40-1.78) 0.65 0.86 (0.36-2.03) 0.73
Lymph node metastasis 4.93 (1.28-19.04) 0.02 4.00 (0.91-17.58) 0.07
Survival status7 1.20 (0.39-3.73) 0.75 1.81 (0.50-6.50) 0.37

*OR: odds ratio with 95% confidence interval; 1Age (per 10 years); 2Tumor localization (gastric cardia; gastric body; gastric antrum); 3Tumor size (≤3 cm; >3 cm and ≤5 cm; >5 cm); 4Differentiation (well or moderate; poor or undifferentiation); 5Tumor invasion (T1; T2; T3; T4); 6TNM stage (I; II; III; IV); 7Survival status (Alive vs. Dead). The cases with 3.61-5.35 mtDNA copies were used as reference.

Zhang et al.

Zhang et al. Diagnostic Pathology 2013 8:173   doi:10.1186/1746-1596-8-173

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