Association of mtDNA copy number with clinicopathological characteristics in gastric cancer. Copy number of mtDNA was analyzed using real-time quantitative PCR approach. The circle represents mtDNA copy number of each case of gastric cancers. Horizonal lines represent mean ± S.E. Sample means were compared using the Mann–Whitney U test. Details are as described in Methods. F, female; M, male; GC, gastric cardia; GA, gastric antrum; GB, gastric body; Well, well/moderate differentiation; Poor, poor/undifferentiation; N, non-lymph node metastasis; Y, lymph node metastasis; ES, early-stage; LS, late-stage.
Zhang et al. Diagnostic Pathology 2013 8:173 doi:10.1186/1746-1596-8-173