GO categories based on biological processes for target genes of dysregulated microRNAs. (A) Target genes of the up-regulated microRNAs were involved in negative regulation of neuron apoptosis, axonogenesis, regulation of synaptic transmission, neurotransmitter secretion et al. (B) Target genes of the down-regulated microRNAs were involved in axonogenesis, synaptic vesicle transport, positive regulation of axon extension et al.
Liu et al. Diagnostic Pathology 2013 8:158 doi:10.1186/1746-1596-8-158